21 August 2016
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Charles Holland Awards for Brave Britons 2016

The Charles Holland Awards for Brave Britons celebrates the achievements of exceptional people from all walks of life, of all ages and from all over the United Kingdom. 

21 August 2016
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New Study Finds Genetic Predisposition for Hearing Loss

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21 June 2016
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New Study Finds Genetic Predisposition for Hearing Loss

A genome-wide association study has found evidence that some people may be more genetically susceptible to noise-induced hearing loss than others.

The study was performed by an international team led by Keck Medicine of the University of Southern California (USC) neuroscientists. While some gene association studies on noise-induced hearing loss in people have been conducted in the past, nothing of this scale has been done before.

Genome-wide association studies, or GWAS, search the entire genome for common genetic variants to see if any of those variants are associated with a specific trait. In the USC study, the team identified the
Nox3 gene, which is almost exclusively found in the inner ear, as a key gene for susceptibility to noise-induced hearing loss.

Using 64 of the 100 strains of mice in the Hybrid Mouse Diversity Panel, the team was able to increase the statistical power of its investigation, leading to the first published GWAS for noise-induced hearing
loss in mice.

USC otologist Rick A Friedman said: "Understanding the biological processes that affect susceptibility to hearing loss due to loud noise exposure is an important factor in reducing the risk.

Source: http://medicalxpress.com/news/2015-04-genetic-predisposition-noise-induced-loss.html

21 June 2016
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